4-Bromo-3-methylaniline
- CasNo:6933-10-4
Product Description
Reputable factory supply 4-Bromo-3-methylaniline 6933-10-4 in stock with high standard
- Molecular Formula: C7H8BrN
- Molecular Weight: 186.051
- Appearance/Colour: grey to brownish crystalline powder
- Vapor Pressure: 0.0389mmHg at 25°C
- Melting Point: 80-82 °C(lit.)
- Refractive Index: 1.609
- Boiling Point: 240 °C at 760 mmHg
- PKA: 4.02±0.10(Predicted)
- Flash Point: 101.2 °C
- PSA： 26.02000
- Density: 1.498 g/cm3
- LogP: 2.92090
4-Bromo-3-methylaniline(Cas 6933-10-4) Usage
InChI:InChI=1/C7H8BrN/c1-5-4-6(9)2-3-7(5)8/h2-4H,9H2,1H3
6933-10-4 Relevant articles
A metal-free aerobic oxidative bromination of anilines and aryl ketones with 2-methylpyridinium nitrate as a reusable ionic liquid
Li, Ming-Fang,Wang, Jian,Ke, Yong-Xin,Pan, Song-Cheng,Yin, Hong,Du, Wenting,Li, Jing-Hua
, p. 267 - 270 (2020/01/08)
An aerobic oxidative bromination of anil...
Sodium sulfate-hydrogen peroxide-sodium chloride adduct: selective protocol for the oxidative bromination, iodination and temperature dependent oxidation of sulfides to sulfoxides and sulfones
Gayakwad, Eknath M.,Patel, Khushbu P.,Shankarling, Ganapati S.
supporting information, p. 6001 - 6009 (2019/04/17)
The regioselective bromination and iodin...
Cu-mediated selective bromination of aniline derivatives and preliminary mechanism study
Zhao, Hong-Yi,Yang, Xue-Yan,Lei, Hao,Xin, Minhang,Zhang, San-Qi
supporting information, p. 1406 - 1415 (2019/05/01)
A simple and efficient bromination of an...
o-xylylene bis(triethyl ammonium tribromide) as a mild and recyclable reagent for rapid and regioselective bromination of anilines and phenols
Hemati, Roya,Shahvelayati, Ashraf S.,Yadollahzadeh, Khadijeh
, p. 682 - 687 (2018/07/14)
Background: o-Xylylene bis(triethyl ammo...
6933-10-4 Process route
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-
7149-70-4
2-bromo-5-nitrotoluene
-
-
6933-10-4
amino-5-bromo-2-toluene
| Conditions | Yield |
|---|---|
|
With
hydrogen;
nickel;
In
methanol;
for 3h;
under 1551.49 Torr;
|
99%
|
|
With
hydrogenchloride; indium;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
|
84%
|
|
With
[RhCl2(p-cymene)]2; dimethylamine borane;
In
tetrahydrofuran;
at 70 ℃;
for 24h;
Inert atmosphere;
Sealed ampoule;
|
82%
|
|
With
decaborane; acetic acid;
palladium on activated charcoal;
In
methanol;
for 0.5h;
Heating;
|
81%
|
|
bei der Reduktion;
|
|
|
With
hydrogenchloride; tin;
|
|
|
With
hydrogenchloride; iron;
|
-
-
108-44-1
1-amino-3-methylbenzene
-
-
6933-10-4
amino-5-bromo-2-toluene
| Conditions | Yield |
|---|---|
|
With
1-hexyl-3-methyl-1-imidazolium bromide; copper(ll) bromide;
for 1h;
regioselective reaction;
|
95%
|
|
With
o-xylylene bis(triethylammonium tribromide);
In
acetonitrile;
at 20 ℃;
for 0.0833333h;
regioselective reaction;
|
95%
|
|
With
4O4S(2-)*8Na(1+)*2H2O2*NaCl; acetic acid; potassium bromide;
at 50 - 52 ℃;
for 5h;
regioselective reaction;
Green chemistry;
|
84%
|
|
With
hydrogen bromide; 2-methylpyridinium nitrate;
at 60 ℃;
for 5h;
Green chemistry;
|
83%
|
|
With
hydrogen bromide; oxygen; 2-methylpyridinium nitrate;
In
water;
at 90 ℃;
for 8h;
|
80%
|
|
With
hydrogen bromide; dimethyl sulfoxide;
at 50 ℃;
for 2h;
|
79%
|
|
With
ethylenebis(N-methylimidazolium) bis(tribromide);
In
dichloromethane;
at 20 ℃;
for 0.5h;
regioselective reaction;
|
75%
|
|
With
acetic acid; potassium bromide;
In
water;
at 20 ℃;
for 1h;
|
70%
|
|
With
N-Bromosuccinimide; N,N-dimethyl-formamide; trichlorophosphate;
at -5 - 39.84 ℃;
for 0.5h;
|
64%
|
|
With
hydrogen bromide; dimethyl sulfoxide;
In
water; ethyl acetate;
at 60 ℃;
for 1h;
|
60%
|
|
With
tetrabutylammomium bromide; copper(ll) bromide;
In
ethanol;
at 25 ℃;
regioselective reaction;
|
55%
|
|
With
bromine;
hydrogen fluoride; antimony pentafluoride;
at -40 ℃;
for 0.5h;
Mechanism;
|
47%
|
|
With
bromine;
hydrogen fluoride; antomony(V);
at -40 ℃;
for 0.5h;
|
47%
|
|
Multistep reaction;
(i) (acetylation), (ii) Br2, AcOH, (iii) aq. HCl;
|
|
|
With
2,6-dimethylpyridine; zeolite 5A; bromine;
|
|
|
With
Oxone; quartz; sodium bromide;
In
n-heptane;
for 0.333333h;
Milling;
|
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