5-Methyluridine
- CasNo:1463-10-1
Product Description
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1.What is the 5-Methyluridine ?
White Powder
5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.
2.What is the CAS number for 5-Methyluridine ?
The CAS number of 5-Methyluridine is 1463-10-1.
3.What are another words for 5-Methyluridine ?
Synonyms?for?5-Methyluridine 1463-10-1:1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione;Uridine,5-methyl-;5-Methyl uridine;Thymine riboside;Methyluridine;5-Methyluridin, Ribothymidine;
4.What is 5-Methyluridine (1463-10-1) used for?
A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.
InChI:InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1
Relevant articles related to 5-Methyluridine:
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SYNTHESIS AND ANTIVIRAL ACTIVITY OF 1-(&β-D-ARABINOFURANOSYL)THYMINE |
Kvasyuk, E. I.,Kulak, T. I.,Tkachenko, O. V.,Mikhaylopulo, I. A.,Zinchenko, A. I.,et al. , p. 493 - 496 (1989) |
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High-yielding cascade enzymatic synthesis of 5-methyluridine using a novel combination of nucleoside phosphorylases |
Visser, Daniel F.,Rashamuse, Konanani J.,Hennessy, Fritha,Gordon, Gregory E.R.,Van Zyl, Petrus J.,Mathiba, Kgama,Bode, Moira L.,Brady, Dean , p. 245 - 253 (2010) |
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Identification of Flavin Mononucleotide as a Cell-Active Artificial N6-Methyladenosine RNA Demethylase |
Xie, Li-Jun,Yang, Xiao-Ti,Wang, Rui-Li,Cheng, Hou-Ping,Li, Zhi-Yan,Liu, Li,Mao, Lanqun,Wang, Ming,Cheng, Liang , p. 5028 - 5032 (2019) |
5.Buy 5-Methyluridine with the best price .
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