Cyclobutanecarbonyl chloride
- CasNo:5006-22-4
Product Description
Chemical plants supply high-quality Cyclobutanecarbonyl chloride 5006-22-4 in bulk
- Molecular Formula: C5H7ClO
- Molecular Weight: 118.563
- Appearance/Colour: clear colourless liquid
- Vapor Pressure: 7.98mmHg at 25°C
- Melting Point: 151-152 °C
- Refractive Index: n20/D 1.455(lit.)
- Boiling Point: 134.7 °C at 760 mmHg
- Flash Point: 42.5 °C
- PSA： 17.07000
- Density: 1.22 g/cm3
- LogP: 1.55190
Cyclobutanecarbonyl chloride(Cas 5006-22-4) Usage
InChI:InChI=1/C5H7ClO/c6-5(7)4-2-1-3-4/h4H,1-3H2
5006-22-4 Relevant articles
A new approach to substituted cyclobutanes: Direct β-deprotonation/magnesiation of cyclobutane carboxamides
Eaton, Philip E.,Zhang, Mao-Xi,Komiya, Naruyoshi,Yang, Cai-Guang,Steele, Ian,Gilardi, Richard
, p. 1275 - 1278 (2003)
BuMgN(i-Pr)2 is shown to be kinetically ...
SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AS FUNGICIDES
-
Page/Page column 98, (2021/12/31)
The present invention relates to substit...
Synthesis of N-trifluoromethyl amides from carboxylic acids
Flavell, Robert R.,Liu, Jianbo,Parker, Matthew F. L.,Toste, F. Dean,Wang, Sinan,Wilson, David M.
supporting information, p. 2245 - 2255 (2021/08/12)
Found in biomolecules, pharmaceuticals, ...
SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE
-
Page/Page column 58; 81, (2020/06/10)
In its many embodiments, the present inv...
Isoalantolactone derivative, pharmaceutical composition and application thereof
-
Paragraph 0014, (2019/02/02)
The invention relates to an isoalantolac...
5006-22-4 Process route
-
-
3721-95-7
Cyclobutanecarboxylic acid
-
-
5006-22-4
Cyclobutanecarbonyl chloride
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
In
toluene;
Heating;
|
100%
|
|
With
thionyl chloride;
at 0 - 90 ℃;
for 1.5h;
Large scale;
|
48.9%
|
|
With
phosphorus trichloride;
|
|
|
With
thionyl chloride;
|
|
|
With
thionyl chloride;
|
|
|
With
thionyl chloride;
In
benzene;
|
|
|
With
thionyl chloride;
for 1h;
Heating;
|
|
|
With
thionyl chloride;
In
dichloromethane;
at 20 ℃;
|
|
|
In
thionyl chloride;
|
|
|
In
thionyl chloride;
|
|
|
With
oxalyl dichloride;
In
N,N-dimethyl-formamide;
for 1.5h;
Reflux;
|
|
|
With
oxalyl dichloride;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
|
|
|
With
oxalyl dichloride;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
|
|
|
With
thionyl chloride;
at 0 ℃;
for 1.5h;
Reflux;
|
|
|
With
oxalyl dichloride;
In
dichloromethane; N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 5h;
Inert atmosphere;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 20 ℃;
for 1h;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
|
|
|
With
pyridine; oxalyl dichloride;
In
dichloromethane; N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 4h;
Inert atmosphere;
|
|
|
With
thionyl chloride;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
Inert atmosphere;
|
|
|
With
oxalyl dichloride;
In
dichloromethane; N,N-dimethyl-formamide;
at 24 ℃;
Inert atmosphere;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 20 ℃;
for 1.5h;
Inert atmosphere;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
for 2h;
|
|
|
With
oxalyl dichloride;
In
dichloromethane; N,N-dimethyl-formamide;
for 2h;
|
|
|
With
thionyl chloride;
In
dichloromethane;
for 6h;
Reflux;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 40 ℃;
for 10h;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 35 ℃;
for 1.5h;
Inert atmosphere;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 ℃;
for 2h;
Inert atmosphere;
|
|
|
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 20 ℃;
|
-
-
7719-09-7
thionyl chloride
-
-
3721-95-7
Cyclobutanecarboxylic acid
-
-
5006-22-4
Cyclobutanecarbonyl chloride
| Conditions | Yield |
|---|---|
|
With
N,N-dimethyl-formamide;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
|
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-
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-
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-
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-
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-
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-
14924-53-9
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-
42392-31-4
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-
5407-98-7
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